1. You should have at least two, preferably three twitter accounts you can sign into and back out of before bothering with http://cotweet.com

2. You should have a couple hundred followers before toying with http://dossy.org/twitter/karma/

3. You should have an installed wordpress blog on your own server before using http://wordpress.org/extend/plugins/fresh-from-friendfeed-and-twitter/

4. You should utilize and donate time and money to http://twitter.pbworks.com/ on a regular and frequent basis… and lastly, perhaps most important of all:

5. You should tie all your twitter account rss feeds through http://feedburner.google.com and rely on Twitter to become a part of your larger web presence cloud.